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When we talk of minoxidil alopecia comes into mind. The two are intertwined and
minoxidil’s fate would have ended earlier without alopecia, consigned to the dustbin of unsuccessful drugs.
Minoxidil was originally used to treat high blood pressure and was about to be discarded due to the serious side
effects it brought on to its patients when it was discovered that one of its side effects had a great potential for
bigger commercial enterprise. One of the side effects saved minoxidil from sure oblivion. People who underwent
minoxidil treatment started growing hairs on different parts of their bodies.
Today, minoxidil is considered as the drug of choice when treating androgenic alopecia
also known as Alopecia aerata and with a couple of other names, too. Minoxidil was granted FDA approval in 1988 for
successfully demonstrating its ability to grow hair on victims of pattern baldness, another name of alopecia
baldness. It started as minoxidil2, which was also available for women’s consumption.
It was successful in growing hair on the crown of the head, and several solutions later,
it did even better by increasing its effect, bringing hair out of the front area of the head and the temple
areas.
Minoxidil, a topical drug, works by blocking the transformation of testosterone in the
skin to its androgenic form called Dihydrotestosterone or DHT. Testosterone exists as natural part of human skin,
since it’s also produced by it and some other organs in the body; the prostate gland for example. But for some
unknown reason, an enzyme converted in it into DHT in some individuals; that’s where the real trouble
begins.
When the DHT components shrink at the end of their growth, they clog the pores of the skin
and with it the cutaneous blood supply of the hair follicle. Minoxidil operates by blocking the creation of DHT.
Without DHT, the cause of the blood vessel’s obstruction is effectively eliminated.
What follows is the task of removing the impediments which brought on the death of hair
follicles. This is done by widening the pathways of the blood vessels, enabling the blood to resupply the affected
areas responsible for hair growth. Nitric oxide, the other important ingredient of minoxidil is the one responsible
for this bringing on this result. This is an important aspect in minoxidil alopecia treatment for without it hair
growth will be impossible.
Minoxidil successfully brings relief to 60% of alopecia victims when used to treat the
abnormality. When used together with other products that are orally consumed the effectiveness of both drugs
increases a lot, allowing customers to experience more hair growth and thicker hair strands.
There are still side effects to annoy its consumers but they allegedly don’t bring on
lasting effect, nor is life threatening. The need to see a doctor to treat some of the side effects is a
possibility. The claim that minoxidil in gel, cream and lotion form bring on only very mild side effects is
heartening to the millions of minoxidil users.
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